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Faculty of Veterinary Science

 
 
Department of Pathology

Introduction

The Department of Pathology fulfills essential role in teaching undergraduate and postgraduate students, along with disease diagnosis in poultry, pets, domestic and wild animals. Pathology provides the critical link between the basic and clinical sciences. The department isdedicated to disseminate the knowledge of diagnosis and control of diseases. Here we emphasize on understanding the pathological mechanisms of infectious diseases caused by bacteria, viruses, parasites and their vectors. Our dynamic faculty includes leading experts in host pathogen interaction, Molecular pathogenesis, Poultry Pathology, Diagnostic and Clinical Pathology.

Our vision is to provide leadership and excellence in disease diagnosis through innovative research and pioneering clinical activity. The outstanding facilities based in the department are second to none providing a range of world class diagnostic services, ensuring best practices and enabling us to provide better and faster results to the clients. The diagnostic services in the department are supported by the teachers, scientists, researchers and postgraduate students who have a vast experience of routine and more complicated clinical cases. We provide routine diagnostic techniques as well as specialized services in areas of hematology, serum biochemistry, cytology, histopathology, immunohistochemistry, endocrinology and postmortem examination. Our primary focus is animal welfare as well as providing the students hands on training and the clients a comprehensive diagnostic laboratory services. Our laboratory reports are accompanied by expert veterinary pathological advice and our pathologists are always available to discuss results or provide further advice according to the clients need. We strive to give same day service for in house tests on samples received during the normal working hours (hematology and serum biochemistry).

Being part of 24/7 extension services of UVAS, we are playing major role by conducting post mortem examination of dead animals at door step, collecting samples to diagnose the disease problem at earliest and giving technical services to treat and control disease problems.

Objectives

The Department of Pathology is focused on producing top quality students as well as professional pathologists for disease diagnosis both in livestock and poultry. The Department is striving to fulfill the following objectives:

  1. Produce highly trained manpower in the field of Pathology.
  2. Improve the quality of education as per needs of government and private sector.
  3. Plan strategies for accurate and early diagnosis of diseases.
  4. Conducting post graduate students research on current disease problems faced by livestock and poultry sector.
  5. Work for effective strategies to control the outbreaks.
  6. Conducting innovative research to develop new molecular techniques for emerging infections.
  7. Ensure the high standards of research work with internal and external quality control and assessments.
  8. Report the test results as soon as they are available by fax, email or by post.
  9. Liaise with other laboratories to provide broad spectrum of tests.
  10. Keep all record for reference and repeat reports if required at no extra cost.

Scope

The scope of Pathology is tremendous. Without an accurate diagnosis, the selection of a course of treatment for a sick animal may be limited. For companion animals, Pathology may mean analysis of blood or urine samples or even tissue biopsies of tumors. In the sphere of veterinary public health, it is vital that notifiable and other communicable diseases are diagnosed quickly and accurately. In research, the understanding of disease processes is important in the development of new treatments. In recent years, the study of the genome has opened a wide range of possibilities in investigating the causes of disease. And the areas of work include, but not limited to, animal diagnostics, teaching and research, pharmaceutical industry, wildlife and environmental conservation, government service, and army and defense. Private companies that produce drugs and insecticides employ pathologists.

Veterinary Pathology provides the reports of basic and applied research involving livestock and poultry. Our focus is to conduct the diagnostic investigations of diseases of animals especially of zoonotic nature. It provides a forum for the understanding of the pathological processes and evaluation of new and existing diagnostic applications of scientific advances and clinical pathologic correlations; fostering the acquisition and maintenance of up­to­date information to ensure high standards of practice; and, encouraging the publication of new information.

Staff Position

Chairman

Prof. Dr. Asim Aslam

Professor

Prof. Dr. Zafar Iqbal Chaudhry
Prof. Dr. Asim Aslam

Associate Professor

Dr. Muhammad Yasin Tipu

Assistant Professors

Dr. Muti-ur-Rehman khan
Dr. Gulbeena Saleem
Dr. Raheela Akhtar
Dr. Muhammad Saeed Imran

Lecturers

Dr. Qamar Un Nisa
Dr. Ishtiaq Ahmed (Ex-Pakistan Leave)

HEC Approved Supervisors

  1. Prof. Dr. Zafar Iqbal Chaudhry
  2. Prof. Dr. Asim Aslam
  3. Dr. Muhammad Yasin Tipu
  4. Dr. Gulbeena Saleem
  5. Dr. Muti ur Rehman Khan
  6. Dr. Raheela Akhtar

Activities of Dept. in Addition to Training & Research

    1. Postmortem examination of large, small animals and Poultry
    2. Hematology
    3. Blood Chemistry
    4. Serum analysis
    5. Histopathology
    6. Urinalysis
    7. Image analysis
    8. Fluorescent Microscopy
    9. PCR

Program/Subject Course Offered

Course No

Title

Credit Hrs

PATH    02302

General Veterinary  Pathology

4(3-1)

PATH    02402

Systemic Veterinary  Pathology

4(3-1)

PATH    02601

Meat Hygiene and Public Health

2(1-1)

PATH    02504

 Veterinary Clinical Pathology

2(0-2)

PATH    02901

Poultry Pathology

3(2-1)

PATH 02602

Forensic Medicine and Jurisprudence

1(1-0)

PATH 02503

Necropsy Practice

1(0-1)

PATH 05605

Clinical Pathology

3(1-2)

PATH 10505

General Pathology

3(2-1)

PATH 10405

Systemic Pathology

3(2-1)

 

Course No

Title

Credit Hrs

PATH    1001

Advanced General Pathology

4(3-1)

PATH    1002

Advanced Clinical Pathology

3(1-2)

PATH    1003

Necropsy Practice

2(0-2)

PATH    1004

Diagnostic Pathology

3(0-3)

PATH    1005

Oncology

3(2-1)

PATH    1006

Pathology of intoxications

3(3-1)

PATH    1007

Canine and Feline Pathology

3(2-1)

PATH    1008

Ruminants Pathology

4(3-1)

PATH    1009

Equine Pathology

3(2-1)

PATH    1010

Camel Pathology

3(2-1)

PATH    1011

Fish Pathology

3(2-1)

PATH    1012

Wildlife Pathology

3(2-1)

PATH    1013

Pathology of infectious diseases of Poultry

4(3-1)

PATH    1014

Pathology of non-infectious diseases of Poultry

3(2-1)

PATH    1015

Food Animal Pathology

3(2-1)

PATH    1016

Immunopathology

3(2-1)

PATH    1017

Molecular Pathobiology

3(2-1)

  Facilities

Principal Equipment

Salient Features/Services

    1. Molecular based diagnostic lab

    2. Automatic Tissue Processor, Cryostat, Auto staining unit

    3. Hematology Analyzer

    4. Chemistry Analyzer

    5. Image Analysis System

    6. Fluorescent Microscope

    7. pH meter, Spectrophotometer

    8. Advanced microscopes attached with cameras and multimedia

    9. Multi Head Microscope
       

    1. Polymerase Chain Reaction for Genetic analysis Bacterial, Viral, and Protozoan Parasites

    2. Histopathology, Automatic Tissue Processing

    3. Cryosectioning, Auto Staining

    4. Hematology

    5. Blood Chemistry Analysis

    6. Immunohistochemistry

    7. Fluorescent Microscopy for chromosomes and cells
      Other Routine Facilities:
      . Postmortem Examination
      . Routine Urine Analysis
      . Detection of Mycobacterium
      . Meat Inspection

Clinical Tests

Liver function Tests (LFT)

  • AST
  • ALT
  • ALP
  • Gamma GT
  • Total and direct bilirubin
  • Total Protein, Albumin

Kidney Funtion tests

  • Urea kinetic
  • Creatinine
  • Random and Fasting Sugar

Recent  Research Publications

  1. S. Shahzad, M. Y. Tipu, A. Aslam, T. Hussain, Z. Ali, S.Y.Shelly, Ziaullah, B. Saleem, A. Yaqub and S.S.Ahmad (2015) Comparative hemato-biochemical study on Theileriosis in naturally infected Punjab Urial and domestic sheep in Pakistan. The Journal of Animal & Plant Sciences, 25(3) 472-476
  2. R. Akhtar, I.Khan, F. Melzer, H. Naubauer,  A.A Anjum, M. Younas, A. Aslam and S. Imran (2015) Differencial anti Brucella activity of bovine and murine macrophages. Accepted in Indian Journal of Experimental Biology.
  3. Umar S, Younus M, Rehman MU, Aslam A, Shah MA, Munir MT, Hussain S, Iqbal F, Fiaz M, Ullah S. 2015. Role of aflatoxin toxicity on transmissibility and pathogenicity of H9N2 avian influenza virus in turkeys. Avian Pathol. 1, 1­22.
  4. Aslam R, Aslam A, Tipu Y, Nazir J, Ghafoor A, Rehmani SF. 2015. Histopathological and immunohistochemical studies for the pathogenesis of a low pathogenicity H9 avian influenza virus in experimentally infected commercial broilers. The Journal of Animal and Plant Science. 25, 45­52.
  5. K. Aziz, M. Nawaz, J. Nazir, A. A. Anjum, T. Yaqub, M. U. Ahmed, M. U. Rehman, G. Aziz and M. Khan. 2015. Isolation, Characterization and Effect of Auxin Producing Bacteria on Growth of Triticum Aestivum. The Journal of Animal & Plant Sciences, 25(4): 2015, Page: 1003-1007
  6. M. Z. Tanveer , A. Javeed , M. Ashraf , M. U. Rehman and M. M. Anjum. 2015. Evaluation of anti-inflammatory and analgesic potential of aqueous methanolic extract of Thuja Orientalis in albino rats. The Journal of Animal & Plant Sciences, 25(4): 2015 Page: 1183-1186
  7. Munir T, Aslam A, Zahid B, Ahmed I, Imran MS, Ijaz M. 2015. Potential of Commonly Resident Wild Birds towards Newcastle Disease Virus Transmission. Pakistan Veterinary Journal. 35, 106­107.
  8. Zahid B, , Aslam A, Saleem G, Imran MS, Younas M. 2015. Effects of immunostimulants on humoral response against infectious bursal disease in broilers. Pakistan Veterinary Journal. 35, 227­230.
  9. Akhtar R, Sardar M, Saima N, Saleem G, Saeed I, Aslam A. 2014. Responses of Nili­Ravi buffalo to aflatoxin B1with and without toxin adsorbents.  The Journal of Animal and  Plant Sciences. 23, 317­323.
  10. Jawad Z, Younus M, Rehman MU, Munir R, Maqbool M, Shahzad W, Masood S, Muhammad K. 2014. Effect of Azadirachtaindica on the hepato­renal functions in broilers chickens. The Journal of Animal and Plant Science. 24, 1022­1018.
  11. Shahzad M, Khan MUR, Aslam A, Younus M, Khan HM, Anjum AA, Masood S. 2014. Dimunition of ochratoxin A and aflatoxin B1 toxicity on hematology and serum biochemistry of Japanese quail (coturnix japonica). The Journal of Animal and Plant Science. 24, 1032­1038.
  12. Rauf M, Chaudhary ZI, Younas M, Anjum AA, Khan HM, Ali MA. 2014. Detection of mycoplasma gallisepticum in experimentally inoculated layer birds by immunohistochemistry. The Journal of Animal and Plant Science. 24, 385­391.
  13. Idrees A, Chaudhary ZI, Younus M, Ashraf K. 2014. Isolation and molecular detection of clostridium chauvoei alpha toxin gene from clinical cases of black quarter disease. The Journal of Animal and Plant Science. 24, 755­757.
  14. Khan MR, Ali I, Jiao W, Wang Y, Masood S, Yousaf MZ, Javaid A, Ahmad S. MeifuFeng. 2014. Ex vivo expansion of functional human UCB­HSCs/HPCs by co culture with AFT024­hkirre cells. Biomed Res Int. 2014; 2014:412075. doi: 10.1155/2014/412075. Epub 2014 Feb 25
  15. Hayat Z, Rehman AU, Akram K, Farooq U, Saleem G. 2014. Evaluation of natural methionine source on broiler growth performance. Journal of Science, Food and Agriculture. Article First published online: 18 NOV 2014. DOI: 10.1002/jsfa.6974
  16. Abbas M, Khan AM, Riffat S, Tipu Y, Nawaz HA, Usman M. 2014. Assessment of sex differences in pharmacokinetics of carvidiol in human. Pakistan Journal of Pharmaceutical Science, 27,1265­1269.
  17. Ahmad HY, Masood S, Zaneb H, Aslam A, Sikandar A, Adil M, Irshad I, Khan K, Tamkeen R. 2014. Comparative effects of organic acids fed diet on morphometry of visceral organs and intestinal histology of two broiler strains. Global Veterinaria 13, 221­226.
  18. Ahmad MS, Maqbool A, Anjum AA, Ahmad, Khan MR, Sultana R, Ali MA. 2014. Occurrence of Hymenolepisdiminutain rats and mice captured from urban localities of Lahore, Pakistan. The Journal of Animal and Plant Science. 24, 392­396.
  19. Ahmad NS, Sana K, Aneeqa SB, Abid S, Akhtar R, Ahmad I, Mukhtar MN, Imran S, Akbar H, Ali S, Usman M. 2014. Rapid detection of Mycobacterium tuberculosis and Rifampicin Resistance in extra pulmonary samples using Gene Xpert MTB/RIF assay. IOSR Journal of Dental and Medical Sciences (IOSR­JDMS). 13, 50­53.
  20. Ahmad M, Ashraf M, Khan MS, Javeed A, Durrani AZ, Altaf I, Khan MR, Ahmed I Avais M. 2014. Clinical and pathological effects of parenterally administered chloroform and aqueous extract of calotropisprocera in rabbits. The Journal of Animal and Plant Science. 24, 57­62.
  21. Sabir S, Anjum AA, Ijaz T, Ali MA, Khan MR, Nawaz M. 2014. Isolation and antibiotic susceptibility of E. coli from urinary tract infections in a tertiary care hospital. Pakistan Journal of Medical Science. 30, 389­392.
  22. Rauf, M, Chaudhary ZI, Younus M, Anjum AA, Khan HM, Ali MA. 2014. Polypeptide mapping and western blot analysis of mycoplasma gallisepticum isolates. The Journal of Animal and Plant Science. 24, 154­158.

Faculty Development

  • Mr.Ishtiaq Ahmad has gone abroad for Ph.D.
  • Prof. Dr. Asim Aslam attended a two days “ International Seminar on Poultry Diseases” at University of Agriculture Faisalabad on 14-15 December 2015.
  • Prof. Dr. Asim Aslam attended the training program on “leadership and change management” held from 27­30th April, 2015 at IBA Karachi under the tertiary education support program of HEC.
  • Prof. Dr. Asim Aslam attended a two days workshop on “Small ruminant value change (SRVC)” under agriculture innovation program funded by USAID on 11­ 12th May held in Islamabad, 2015.

Co-curricular Activities

  • Study tour of undergraduate students to Slaughter house to examine and learn gross lesions of various diseases.
  • Annual dinner of department of Pathology arranged at Salt n pepper , Lahore
  • Post –Graduate study tour to A.W. Chicks Hatchery and Farms in District Kasur.

Invited Lectures

  1. Prof. Dr. Ashiq Hussain Cheema demonstrated  histopathological slides of various disease conditions.
  2. Dr. Asif Latif Manager Big Feed gave presentation on modern practices in broiler farming in controlled shed rearing system.
  3. Dr. Muhammad Raza Younus Manager Hi-Tech Feed delivered lectures on Poultry industry modernization and disease control strategies in Pakistan

Measures taken to Enhance the Academics

    1. Up-gradation of Labs & Lecture rooms.
    2. Thirteen latest Olympus microscopes added in under graduate Lab.
    3. Addition of Chemistry and hematology Analyzer in Hematology Lab.
    4. Renovation of incineration facility in the Postmortem block.

  Induction of Modern Equipment

    1. Fluorescent Microscopy & Image Analysis System.
    2. Establishment of Molecular Pathology Laboratory
    3. Establishment of Poultry Diagnostic Laboratory in Postmortem Teaching Block

Other Activity

Department of Pathology in collaboration with Higher Education Commission has organized three day workshop on “Recent Advances in Necropsy Practice in Livestock  and Poultry and its Vetro-Legal Implications” held on 25 to 27 Feb, 2015 at Conference Hall, UVAS, Lahore.

Research Priorities

  1. Development of advanced molecular diagnostic techniques for various infectious diseases
  2. Pathology and pathogenesis of various diseases of zoonotic importance
  3. Understanding the pathological mechanisms of infectious diseases caused by bacteria, viruses, parasites, and their vectors
  4. Developing novel approaches in the research of host-pathogen interaction and exploring its molecular pathogenesis for various infectious diseases.
  5. Studies on pathological effects of drugs/heavy metals/indigenous plants/ fungal toxins in animals and poultry
  6. Pathology and pathogenesis of infectious and non-infectious diseases of poultry
  7. Building bridge between basic research and in vivo application using animal models

 

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Prof. Dr. Asim Aslam