Contact information
Assistant Professor
2018
PhD (Pharmacology)
China Pharmaceutical University Nanjing, China
Thesis title: Drp1-associated mitochondrial injury is linked with triptolide-induced hepatotoxicity
2014
M.Phil. (Pharmacology)
University of Agriculture Faisalabad, Pakistan
Thesis title: Determination of Doxycycline residues in broiler liver and meat by HPLC-UV
2012
Pharm-D
GC University Faisalabad, Pakistan
Biography
I am a Pharmacologist with research experience in Toxicology. I have developed skills in drug toxicity, in vitro toxicology, in vivo toxicology, hepatotoxicity, nephrotoxicity, and mitochondrial toxicity. I have acquired good communication, organizational, and interpersonal skills and excellence in writing scientific reports and publications, project proposals, and presenting posters and seminars.
Area of Interest
Pharmacology and Toxicology
Publications
- Hasnat M, Yuan Z, Naveed M, Khan A, Raza F, Xu D, Ullah A, Sun L, Zhang L and Jiang Z. Drp1-associated mitochondrial dysfunction and mitochondrial autophagy: a novel mechanism in triptolide-induced hepatotoxicity 2019. Cell biology and toxicology: 1-14.
- Hasnat M, Yuan Z, Ullah A, Naveed M, Raza F, Baig MMFA, et al. Mitochondria-dependent apoptosis in triptolide-induced hepatotoxicity is associated with the Drp1 activation. Toxicology Mechanisms and Methods. 2020;30(2):124-33.
- Yuan Z, Yuan Z, Hasnat M, Zhang H, Liang P, Sun L, et al. A new perspective of triptolide-associated hepatotoxicity: the relevance of NF-κB and NF-κB-mediated cellular FLICE-inhibitory protein. Acta Pharmaceutica Sinica B. 2020.
- Yuan Z, Zhang H, Hasnat M, Ding J, Chen X, Liang P, et al. A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation. Toxicology 2019.
- Naveed M, Han L, Hasnat M, Baig MMFA, Wang W, Mikrani R, et al. Suppression of TGP on myocardial remodeling by regulating the NF-κB pathway. Biomedicine & Pharmacotherapy 2018;108:1460-8.
- Naveed M, Phil L, Sohail M, Hasnat M, Baig MMFA, Ihsan AU, et al. Chitosan oligosaccharide (COS): An overview. International Journal of Biological Macromolecules 2019.
- Raza F, Zhu Y, Chen L, Khan A, Khan MW, Hasnat M, Zafar H, Han H, Wu J, Ge L. Paclitaxel loaded pH responsive Hydrogel based on self assembly peptides for tumor tageting: Biomaterials Science (RSC) 2019.
- Asifullah K, Zhou Z, He W, Gao K, Khan MW, Faisal R, et al.CXCR4- receptor targeted liposomes for the treatment of peritineal fibrosis. Molecular pharmaceutics. 2019.
- Yuan Z, Hasnat M, Liang P, Yuan Z, Zhang H, Sun L, et al. The role of inflammasome activation in Triptolide-induced acute liver toxicity. International immunopharmacology. 2019;75:105754.
- Shi L, Yuan Z, Liu J, Cai R, Hasnat M, Yu H, et al. Modified Simiaowan prevents articular cartilage injury in experimental gouty arthritis by negative regulation of STAT3 pathway. Journal of ethnopharmacology 2021;270:113825.
- Pervaiz I, Hasnat M, Ahmad S, Khurshid U, Saleem H, Alshammari F, et al. Phytochemical composition, biological propensities, and in-silico studies of Crateva adansonii DC.: A natural source of bioactive compounds. Food Bioscience 2022;49:101890.
- Wu Q, Li L, Miao C, Hasnat M, Sun L, Jiang Z, et al. Osteopontin promotes hepatocellular carcinoma progression through inducing JAK2/STAT3/NOX1-mediated ROS production. Cell death & disease 2022;13:1-12.
- Hou S, Hasnat M, Chen Z, Liu Y, Baig MMFA, Liu F, et al. Application Perspectives of Nanomedicine in Cancer Treatment. Frontiers in Pharmacology 2022;13.
- Title: Cytotoxicity caused by triptolide in HepG2 liver cancer cell line
Event: 2nd International Pharmacy Conference and Exhibition Department of Pharmacy, IUB Bahawalpur, 2020
- Title: Hepatotoxicity by pyrazinamide
Event: One Health Conference, UVAS, 2021
- Title: Induction of Hepatotoxicity by Anti-Tb Drug Disturbed the Mitochondrial Function
Event: Second International Congress on Biological and Health Sciences, Turkey, 2022