![Dr. Muhammad Saad Khilji](https://uvas.edu.pk/website/wp-content/uploads/2022/06/Dr.-Muhammad-Saad-Khilji.jpg)
Contact information
Email: saad.khilji@uvas.edu.pk
Cell: +92 343 5006343
Phone: +92 42 99211449
Ext. 435
Dr. Muhammad Saad Khilji
Lecturer
DVM, M.Phil, Ph.D.
Biography
Muhammad Saad Khilji is part of the Department of Physiology, UVAS since 2017. He served as Teaching Assistant and later as a lecturer in the same Department. He received his bachelor’s degree (DVM) from Pir Mehr Ali Shah – Arid Agriculture University, Rawalpindi and masters (Physiology) from the University of Veterinary and Animal Sciences, Lahore. He resumed his position after completing his Ph.D. (Physiology) from the University of Copenhagen, Denmark under the Chief Minister Merit Scholarship Program, an initiative of The Punjab Educational Endowment Fund.
Area of Interest
- Stress Physiology
- Cell Physiology
- The intersection of endoplasmic reticulum stress and inflammation
- Diabetology
- Cross talk between the immune and endocrine system
Publications
Research Publications
Conference Papers
Book Chapter
Research Publications
2022
- Muhammad S. Khilji., Faridi, P., Pinheiro-Machado, E., Hoefner, C., Dahlby, T., Aranha, R., S. Buus., M. Nielsen., J. Klusek., T. Mandrup-Poulsen., K. Pandey & Marzec, M. T. (2022). Defective proinsulin handling modulates the MHC I bound peptidome and activates the inflammasome in β-cells. Biomedicines, 10(4), 814. [More information]
2020
- Muhammad S. Khilji., D. Verstappen, T. Dahlby, M. C. B. Prause, C. Pihl, S. E. Bresson, T. H. Bryde, K. Klindt, Zivkovic, M. Bousquet-Dubouch, B. Tyrberg, T. Mandrup-Poulsen, M. T. Marzec (2020). The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, non-toxic concentrations of interleukin 1 β, PLOS ONE, 15.2 (2020): e0222432 [More information]
- Muhammad S. Khilji., D. Verstappen, T. Dahlby, S. E. Bresson, T. H. Bryde, C. Pihl, K. Klindt, Zivkovic, M. Bousquet-Dubouch, B. Tyrberg, T. Mandrup-Poulsen, M. T. Marzec (2020). The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94 deficient β cells and is overexpressed in type 2 diabetes pancreatic islets. American Journal of Physiology – Endocrinology & Metabolism. 318.6 (2020): E892-E900 [More information]
2019
- Seyed M. Ghiasi, T. Dahlby, Caroline H. Andersen, L. Haataja, S. Petersen, Muhmmad omar-hmeadi, M Yang, C. Pihl, Sophie E. Bresson, Muhammad S. Khilji, K. Klindt, O. Cheta, Marcelo J. Perone, B. Tyrberg, C. Prats, S. Barg, A. Tengholm, P. Arvan, T. Mandrup-poulsen and Michal T. Marzec. The Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 is Essential for Proinsulin Handling, Diabetes, db180671. [More information]
2018
- Hafiz F. Rehman, H. Zaneb, S. Masood, Muhammad. S. Yousaf, S. Ashraf, I. Khan, M. Shah, Muhammad S. Khilji and Habib U. Rehman,. Effect of Moringa oleifera leaf powder supplementation on pectoral muscle quality and morphometric characteristics of tibia bone in broiler chickens. Brazilian Journal of Poultry Science, 2018; 20(4): 817-824. [More information]
- Muhammad S. Khilji, Muhammad S. Yousaf, Abdullah A. Saeed, Habib U. Rehman, H. Zaneb, and Muhammad A. Rashid. Differential effects of hyperthyroidism on declined immunity of broiler chicken. Journal of Animal Physiology and Animal Nutrition, 2018. 102(2): e948-e956. [More information]
2017
- Abdullah A. Saeed, Mansur A. Sandhu, Muhammad S. Khilji, Muhammad S. Yousaf, Habib U. Rehman, Zafar I. Tanvir, and Tanveer Ahmad. Effects of dietary chromium supplementation on muscle and bone mineral interaction in broiler chicken. Journal of Trace Elements in Medicine and Biology, 2017; 42 25-29. [More information]
2014
- Mansur A. Sandhu, Abdullah A. Saeed, Muhammad S. Khilji, Riaz H. Pasha and Nasir Mukhtar, Ontogenic development of corticotrophs in fetal buffalo (Bubalus bubalis) pituitary gland, European Journal of Histochemistry, 2014; 58 (2292): 11-14. [More information]
2013
- Mansur A. Sandhu, Abdullah A. Saeed, Muhammad S. Khilji, Anwaar Ahmed, Malik Shah Z. Latif and Nauman Khalid, Genotoxicity Evaluation of Chlorpyrifos: A Gender Related Approach in Regular Toxicity Testing, The Journal of Toxicological Sciences, 2013;38(2):237-44. [More information]
Conference Papers
- S. Khilji, E. Pinheiro-Machado, T. Dahlby, R. Aranha, S. Buus, M. Nielsen, P. Faridi, A. W. Purcell, T. Mandrup-Poulsen, M. T. Marzec, Defective proinsulin handling modulates the MHC I bound peptidome and activates the inflammasome in β-cells, DDA Winter School for Postdocs, November 2021, Malaga, Spain.
- N. Tiedemann, T. B. Holgersen, C. Pihl, M. S. Khilji, H. A. Hotiana, M. T. Marzec, FK-506 Binding Protein 2: A potential novel proinsulin folding factor, Biomedicinsk Institut day, October 2021, Copenhagen, Denmark.
- S. Khilji, D. Verstappen, T. Dahlby, S. E. Bresson, M. Bousquet-Dubouch, B. Tyrberg, T. Mandrup-Poulsen, M. T. Marzec, Non-standard proteasomes are active in beta cells and further increased in GRP94 deficient beta cells and type 2 diabetes, Copenhagen Bioscience Conference 18 – Metabolism in Action – central and peripheral control of energy metabolism, October 2019, Hillerød, Denmark.
- S. Khilji, D. Verstappen, T. Dahlby, S. E. Bresson1, M. Bousquet-Dubouch, B. Tyrberg, T. Mandrup-Poulsen, M. T. Marzec, Non-standard proteasomes are constitutively expressed in beta cells and upregulated by low dose of interleukin 1-beta, Danish Diabetes Academy Training, October 2019, Boston, USA.
- S. Khilji, D. Verstappen, T. Dahlby, T. Mandrup-Poulsen, M.T. Marzec, Mishandled proinsulin is degraded via non-standard proteasomes in GRP94 deficient beta cells, Danish Diabetes Academy Summer School on Diabetes and Metabolism for PhD Students, August 2019, Helnæsvej, Ebberup, Denmark.
- S. Khilji, D. Verstappen, C. K. Nielsen, C. Pihl, S. E. Bresson, T. H. Bryde, S. M. Ghiasi, T. Mandrup-Poulsen, M. T. Marzec, Constitutive expression of non-standard proteasomes and its further upregulation in insulin producing cells with low dose of Interleukin 1-β, 3rd Joint EASD Islet Study Group meeting and Beta-Cell Workshop, April 2019, University of Oxford, England.
- S. Khilji, Mansur A. Sandhu, Abdullah A. Saeed, Riaz H. Pasha and Mujeeb R. Sahoo, Immune Response of Meat Type Chicken During Extreme Weather Stress, 33rd Pakistan Congress of Zoology, April 2013, National Heritage Museum, Islamabad, Pakistan.
- Abdullah A. Saeed, Mansur A. Sandhu, S. Khilji, Mohsin Raza and Nasir Mukhtar, Metabolic and stress hormones regulation during environmental stress, 33rd Pakistan Congress of Zoology, April 2013, National Heritage Museum, Islamabad, Pakistan.
- Abdullah A. Saeed, S. Khilji, Mansur A. Sandhu, Chlorpyrifos induced blood lymphocytes DNA aberrations in rats. National Science Conference, January 2012, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan.
Book Chapter
GRANTS AND AWARDS
GRANT | AMOUNT |
Chief Minister Merit Scholarship for Ph.D. – The Punjab Educational Endowment Fund, Pakistan | |
Private Foundations for purchase of lab equipment (OMIX application) (group member) | 3,400,000 DKK |
Travel grant – Eva og Hans Carl Adolf Holms Minde legat | 1,500 DKK |
Travel grant – Danish Diabetes Academy training at Boston, USA | 5,000 DKK |
Travel grant for EASD postgraduate course in Cairo, Egypt (secured but did not avail) | 3,000 DKK |
Travel grant for Copenhagen Bioscience Conference, Copenhagen, Denmark (secured but did not avail) | 2,000 DKK |
Travel grant – Christian og Ottilia Brorsons rejselegat for yngre videnskabsmænd - og kvinder | 15,000 DKK |
Change of research environment grant, University of Copenhagen | 45,000 DKK |
TRAINING COURSES ORGANIZED
- Organizer in two days workshop Skills Enhancement of Teaching Staff of LSTCs/Training Institutes at the University of Veterinary and Animal Sciences, Lahore (30th and 31st March 2017)
- Organizer in Hands-on Training on Macrophage Isolation from Mice at the University of Veterinary and Animal Sciences, Lahore (20th April 2016)
- Organizer in two days 2nd International Symposium on Electrophysiology at the University of Veterinary and Animal Sciences, Lahore (2nd & 4th December 2015)
TRAINING COURSES ATTENDED
- Nature MasterClasses online course organized by the University of Copenhagen, Denmark (1st February 2021 – 28th January 2022)
- Career PhD student talk (online) course organized by the University of Copenhagen, Denmark (14th December 2021)
- Winter School for Postdocs organized by Danish Diabetes Academy, Denmark, held at Malaga, Spain (7th – 12th November 2021)
- Basal Metabolism and Molecular Mechanisms in Diabetes organized by the Danish Diabetes Academy, Denmark (26th – 28th October 2021)
- eLearning course – Diagnosis of type 1 diabetes organized by the European Association for the Study of Diabetes (10th February 2021)
- Online course – Zotero introduction course for researchers, PhD students and postdocs organized by the University of Copenhagen, Denmark (9th February 2021)
- CRISPR Tsunami organized by the University of Copenhagen, Copenhagen, Denmark (10th September 2021)
- Less stress – better performance (online) organized by the University of Copenhagen, Copenhagen, Denmark (28th January 2021)
- Studying abroad – afternoon workshop (online) organized by the University of Copenhagen, Denmark (30th November 2020)
- eLearning course – The pathogenesis of type 1 diabetes (module 2) organized by the European Association for the Study of Diabetes (21st August 2020)
- eLearning course – The pathogenesis of type 1 diabetes (module 1) organized by the European Association for the Study of Diabetes (20th August 2020)
- Studying abroad – afternoon workshop at the University of Copenhagen, Copenhagen, Denmark (4th December 2019)
- Kaj-Ulrik Linderstrøm-Lang Symposium organized by the University of Copenhagen, Copenhagen, Denmark (12th November 2019)
- Danish Diabetes Academy training day organized by Danish Diabetes Academy, Denmark, held at Boston, USA (23rd October 2019)
- Summer School on Diabetes and Metabolism organized by Danish Diabetes Academy, Denmark (26th – 29th August 2019)
- Basal Metabolism and Molecular Mechanisms in Diabetes organized by the Danish Diabetes Academy, Denmark (26th – 29th November 2018)
- Certification by Federation of European Laboratory Animal Science Associations Credential ID ABD-F032/10/18-98, Copenhagen, Denmark (30th April 2018)
- Two days workshop on ‘LaTeX’ at the University of Veterinary and Animal Sciences, Lahore, Pakistan (23rd & 24th May 2017)
- Five days workshop on ‘Data Analytical Model Building and Proposal/Project Development’ at the University of Veterinary and Animal Sciences, Lahore, Pakistan (13th – 17th December 2016)
- In-service Training for Faculty at the University of Veterinary and Animal Sciences, Lahore, Pakistan (1st – 5th August 2016)
- Two Day Workshop on “Applied Biostatistics” at the University of Veterinary and Animal Sciences, Lahore, Pakistan (26th & 27th May 2015)
- One day International Workshop on Electrophysiology at the University of Veterinary and Animal Sciences, Lahore, Pakistan (21st November 2014)
- One-day Seminar on ‘Lipidemia and Human Health’ by Prof. Dr. Khadija Ouguerram (University of Nantes, France) at the University of Veterinary & Animal Sciences, Lahore, Pakistan (24th March 2014)