Dr. Muhammad Irfan Siddique

Assistant Professor
Pharm. D (BMU, Pakistan), MS Pharmaceutics (Greenwich University, London), PhD (UKM, Malaysia)
Tel: 00 92 42 9921 1449-50 (Ext 309)
Mobile:
Email: irfan.siddique@uvas.edu.pk

To date, Dr. Muhammad Irfan Siddique has more than eleven years of job experience in quality control, teaching, and research/development. He started his carrier as a Quality Control Analyst in Kolak snack Foods London, UK. During his master from Greenwich University London got experience working in the local pharmacy. In 2012, he started his teaching and research career at Lahore College of Pharmaceutical Sciences, Lahore, Pakistan. After submitting his Ph.D. research thesis, he joined Akhtar Saeed College of Pharmaceutical Sciences in Oct.2016, affiliated with the University of Punjab.
His main area of research is the development of nanoparticle-based formulation. To date, he has published various research papers in ISI-cited journals with a good impact factor. Dr. Muhammad Irfan Siddique joined UVAS in August 2017 as an Assistant Professor at the Institute of Pharmaceutical Science.

Area of Interest

  • Nano-encapsulation
  • Targeted Drug Delivery
  • Topical Drug Delivery system

Publications


 

  1. Qurrat-ul-ain Khan, Muhammad Irfan Siddique*, Fatima Rasool, Muhammad Naeem, Muhammad Usman & Muhammad Zaman Development and characterization of orodispersible film containing cefixime trihydrate. Drug Development and Industrial Pharmacy, I.F. 2.365
  2. Ahmad Z, Khan MI, Siddique MI, Sarwar HS, Shahnaz G, Hussain SZ, Bukhari NI, Hussain I, Sohail MF. Fabrication and Characterization of Thiolated Chitosan Microneedle Patch for Transdermal Delivery of Tacrolimus. AAPS PharmSciTech. 2020 Feb;21(2):1-2. AAPS PharmSci Tech. I.F 2.401.
  3. Wardah Ashfaq, Khurram Rehman, Muhammad Irfan Siddique & Qurrat-Al-Ain Khan. Eicosapentaenoic Acid and Docosahexaenoic Acid from Fish Oil and Their Role in Cancer Research. Food review international. I.F. 4.113.
  4. Siddique MI, Saima Tufail, Ze Heng Ker, Tahir Mehmood Khan, Fatima Rasool, Muhammad Farhan Sohail and Nabeel Shahid. Towards fast and cost-effective up-scaling of Nano-encapsulations by Ionic-gelation method using model drug for the treatment of atopic dermatitis. PJPS I.F. 0.562.
  5. Muhammad Ijaz Riaz, Hafiz Shoaib Sarwar, Mubashir Rehman, Umar Farooq Gohar, Syed Atif Raza, Muhammad Irfan Siddique, Gul Shahnaz, Muhammad Farhan Sohail. Study of erythrocytes as a novel drug carrier for the delivery of artemether. BJPS I.F. 0.814.
  6. Siddique MI, Katas H, Amin MC, Ng SF, Zulfakar MH, Buang F, Jamil A, Syed Maaz Nadeem. Potential treatment of atopic dermatitis: tolerability and safety of cream containing nanoparticles loaded with hydrocortisone and hydroxytyrosol in human subjects. Drug Delivery and Translational Research, I.F. 2.664.
  7. Siddique MI, Nabeel shahida, Zunera Razzaqa, Haliza Katasb, Muhammad khurram waqasa, Kashif-ur-Rahmana. Fabrication and characterization of Matrix Type Transdermal Patches Loaded with Tizanidine Hydrochloride: Potential Sustained Release Delivery System. Drug Development and Industrial Pharmacy, I.F. 2.365
  8. Siddique MI, Haliza Katas, Chai Yi Wen, Zahid Hussain, and Fatin Hanini Mohd Fadhil. Thermoresponsive curcumin/DsiRNA nanoparticle gels for the treatment of diabetic wounds: synthesis and drug release Therapeutic Delivery, March 2017 ,Vol. 8, No. 3 , Pages 137-150 (doi: 10.4155/tde-2016-0075).
  9. Siddique MI, Katas H, Amin MC, Ng SF, Zulfakar MH, Buang F, Jamil A. Preclinical Safety Evaluation of Hydrocortisone-hydroxytyrosol Co-loaded Chitosan Nanoparticles Cream in Albino Wistar Rats. Proceedings of pharmaceutical sciences research day 2015. 2015:102.
  10. Siddique MI, Katas H, Amin IM, Cairul M, Ng SF, Zulfakar MH, Buang F, Jamil A. Minimization of Local and Systemic Adverse Effects of Topical Glucocorticoids by Nanoencapsulation: In Vivo Safety of Hydrocortisone–Hydroxytyrosol Loaded Chitosan Nanoparticles. Journal of pharmaceutical sciences. 2015 Dec 1; 104(12):4276-86. I.F. 2.997
  11. Siddique MI, Katas H, Amin MC, Ng SF, Zulfakar MH, Jamil A. In-vivo dermal pharmacokinetics, efficacy, and safety of skin targeting nanoparticles for corticosteroid treatment of atopic dermatitis. International journal of pharmaceutics. 2016 Jun 30; 507(1):72-82. I.F: 4.845.

 

  1. Muhammad Irfan Siddique, Preparation and Physicochemical characterization of Orodispersible Film Containing Insoluble Drug Molecule, Two-day One health international conference 25-26th  November 2020. College of Veterinary & Animal Sciences, Jhang.
  2. Muhammad Irfan Siddique, Development and Characterization of Simvastatin Loaded Chitosan Nanoparticles for its Potential Effect on Diabetic Wound Healing’’. Webinar Recent Advancement in Miniaturized Drug Delivery System 28th October 2020. International Medical University, Malaysia.
  3. Muhammad Irfan Siddique, Molecular characterization of drug-loaded chitosan nano-particles’’. Recent Advances in pharmaceutical research, 3rd September 2020. COMSAT University Islamabad, Pakistan.
  4. Muhammad Irfan Siddique, Development and Characterization of Tizanidine Hydrochloride Loaded Transdermal Patch. International Pharmacy Conference & Exhibition IPCE-2020 (Islamia University Bahawalpur, Pakistan.
  5. Muhammad Irfan Siddique, Preparation and Characterization of Curcumin Loaded Chitosan Nanoparticles in Sodium Alginate Based Gel. International Pharmacy Conference (Lahore College for Women University-2019).
  6. Muhammad Irfan Siddique, Preparation and Characterization of Glucocorticoids Loaded Nano-particles and its Antibacterial Activity. International Pharmacy Scientific Symposium, University of Central Punjab-2019).
  7. Muhammad Irfan Siddique, Nanotechnology in Dermatology. “Nanotechnology, The Future of Medicine” Lahore College of Pharmaceutical Sceinces-2019).
  8. Muhammad Irfan Siddique*1,2, Haliza Katas2, Mohd Cairul Iqbal Mohd Amin2. Scaling-up the nano-fabrication and stability study of hydrocortisone and hydroxytyrosol co-loaded chitosan nano-particles. Advances in Phytochemical Analysis (Trends in Natural Products Research, Liverpool, United Kingdom)-2018.
  9. Muhammad Irfan Siddique*1,2, Haliza Katas2, Mohd Cairul Iqbal Mohd Amin2. Preparation of drug loaded nano-particle on large scale and its characterization for the treatment of atopic dermatitis. Pharmaceutical and Biochemical Sciences (PBS) 7th Pak Pharma. & Healthcare EXPO 2018.
  10. Muhammad Irfan Siddique*1,2, Haliza Katas2, Mohd Cairul Iqbal Mohd Amin2. Preparation of drug loaded nano-particle on large scale and its characterization for the treatment of atopic dermatitis. Pharma Asia, PPMA 2018.
  11. Muhammad Irfan Siddique*1,2, Haliza Katas2, Mohd Cairul Iqbal Mohd Amin2. Fabrication of chitosan nano-particles for boosting transdermal delivery of topical glucocorticoids: in-vivo permeation and pharmacokinetic assessment. 3rd International Health Trigon Summit 2018.
  12. Muhammad Irfan Siddique*1,2, Haliza Katas2, Mohd Cairul Iqbal Mohd Amin2. Safe and non-irritant cream containing hydrocortisone and hydroxytyrosol co-loaded chitosan nano-particles: Acute dermal toxicity and irritation studies. National Conference on Recent Advancement in Pharmaceutical Sciences 2018.
  13. Muhammad Irfan Siddique*1, Haliza Katas1, Mohd Cairul Iqbal Mohd Amin1. Clinical Investigation and Biocompatibility of Encapsulated Topical Glucocorticoids. International conference on recent advances in clinical research-2017. UVAS, Lahore
  14. Muhammad Irfan Siddique*1, Haliza Katas1, Mohd Cairul Iqbal Mohd Amin1, Ali Naim2. Development of chitosan nano-particles of hydrocortisone-hydroxytyrosol for targeted delivery and safety in albino Wistar rats. International pharmacy conference and exhibition, 2016.
  15. Muhammad Irfan Siddique*1, Haliza Katas1, Mohd Cairul Iqbal Mohd Amin1, Shiow-Fern Ng1, Mohd Hanif Zulfakar1, Fhataheya Buang1, Adawiyah Jamil2. In-Vivo Dermal Pharmacokinetics, Efficacy, and Safety of Skin Targeting Nanoparticles for Corticosteroid Treatment of Atopic Dermatitis. Pharmaceutical science Research day 2016.
  16. Muhammad Irfan Siddique1, Haliza Katas1, Mohd Cairul Iqbal Mohd Amin1, Shiow-Fern Ng1, Mohd Hanif Zulfakar1, Fhataheya Buang1, Adawiyah Jamil2. Nano-particles Enhance Targeted Topical Corticosteroids Delivery into the Skin with Improved Safety for the Treatment of Atopic Dermatitis: In-Vivo Safety of Hydrocortisone-Hydroxytyrosol Loaded Chitosan Nanoparticles. Control release and drug delivery symposium, 2015.
  17. Muhammad Irfan Siddique1, Haliza Katas1*, Mohd Cairul Iqbal Mohd Amin1, Shiow-Fern Ng1, Mohd Hanif Zulfakar1, Fhataheya Buang1, Adawiyah Jamil2 Preclinical safety evaluation of hydrocortisone-hydroxytyrosol co-loaded chitosan nano-particles cream in albino Wistar rats. Pharmaceutical science Research day 2015.
  18. Muhammad Irfan Siddique*, Haliza Katas, Mohd Cairul Iqbal Mohd Amin. Acute dermal toxicity and acute dermal irritation of hydrocortisone-hydroxytyrosol chitosan nano-particles in albino wistar rat skin. Control release and drug delivery symposium, 2014

 

 

Participation and presentation at international scientific event

  1. Muhammad Irfan Siddique*, Haliza Katas, Mohd Cairul Iqbal Mohd Amin. Acute dermal toxicity and acute dermal irritation of hydrocortison-hydroxytyrosol chitosan nanoparticles in albino wistar rat skin. Control release and drug delivery symposium, 2014.
  2. Muhammad Irfan Siddique1, Haliza Katas1*, Mohd Cairul Iqbal Mohd Amin1, Shiow-Fern Ng1, Mohd Hanif Zulfakar1, Fhataheya Buang1, Adawiyah Jamil2 Preclinical safety evaluation of hydrocortisone-hydroxytyrosol co-loaded chitosan nanoparticles cream in albino Wistar rats. Pharmaceutical science Research day 2015.
  3. Muhammad Irfan Siddique1, Haliza Katas1, Mohd Cairul Iqbal Mohd Amin1, Shiow-Fern Ng1, Mohd Hanif Zulfakar1, Fhataheya Buang1, Adawiyah Jamil2. Nanoparticles Enhance Targeted Topical Corticosteroids Delivery into the Skin with Improved Safety for the Treatment of Atopic Dermatitis: In-Vivo Safety of Hydrocortisone-Hydroxytyrosol Loaded Chitosan Nanoparticles. Control release and drug delivery symposium, 2015.
  4. Muhammad Irfan Siddique*1, Haliza Katas1, Mohd Cairul Iqbal Mohd Amin1, Shiow-Fern Ng1, Mohd Hanif Zulfakar1, Fhataheya Buang1, Adawiyah Jamil2. In-Vivo Dermal Pharmacokinetics, Efficacy, and Safety of Skin Targeting Nanoparticles for Corticosteroid Treatment of Atopic Dermatitis. Pharmaceutical science Research day 2016.
  5. Muhammad Irfan Siddique*1, Haliza Katas1, Mohd Cairul Iqbal Mohd Amin1, Ali Naim2. Development of chitosan nanoparticles of hydrocortisone-hydroxytyrosol for targeted delivery and safety in albino Wistar rats. International pharmacy conference and exhibition, 2016.
  6. Muhammad Irfan Siddique*1, Haliza Katas1, Mohd Cairul Iqbal Mohd Amin1. Clinical Investigation and Biocompatibility of Encapsulated Topical Glucocorticoids. International conference on recent advances in clinical research-2017. UVAS, Lahore
  7. Muhammad Irfan Siddique*1,2, Haliza Katas2, Mohd Cairul Iqbal Mohd Amin2. Safe and non-irritant cream containing hydrocortisone and hydroxytyrosol co-loaded chitosan nanoparticles: Acute dermal toxicity and irritation studies. National Conference on Recent Advancement in Pharmaceutical Sciences 2018.
  8. Muhammad Irfan Siddique*1,2, Haliza Katas2, Mohd Cairul Iqbal Mohd Amin2. Fabrication of chitosan nanoparticles for boosting transdermal delivery of topical glucocorticoids: in-vivo permeation and pharmacokinetic assessment. 3rd International Health Trigon Summit 2018.
  9. Muhammad Irfan Siddique*1,2, Haliza Katas2, Mohd Cairul Iqbal Mohd Amin2. Preparation of drug loaded nano-particle on large scale and its characterization for the treatment of atopic dermatitis. Pharma Asia, PPMA 2018.
  10. Muhammad Irfan Siddique*1,2, Haliza Katas2, Mohd Cairul Iqbal Mohd Amin2. Preparation of drug loaded nano-particle on large scale and its characterization for the treatment of atopic dermatitis. Pharmaceutical and Biochemical Sciences (PBS) 7th Pak Pharma. & Healthcare EXPO 2018.
  11. Muhammad Irfan Siddique*1,2, Haliza Katas2, Mohd Cairul Iqbal Mohd Amin2. Scaling-up the nano-fabrication and stability study of hydrocortisone and hydroxytyrosol co-loaded chitosan nanoparticles. Advances in Phytochemical Analysis (Trends in Natural Products Research, Liverpool, United Kingdom)-2018.

Graduate Student Supervision

Under Supervision:

  • 06 M. Phil students as Supervisor
  • 02 M. Phil. Students as Major Member

Projects

Author(s) and brief title of grant

Funding body / Investigator

Year

Value

  1. In-vitro, in-vivo correlation of transdermal nanofilm containing topical glucocorticoid

Higher Education Commission of Pakistan

2017-18

0.5 Million Pakistani Rupee

Conferences / workshops Organized

  1. Pharmconvention-2019, Organized by Institute of Pharmaceutical Sciences, UVAS, Lahore

Conferences / workshops participated

  1. UVAS Technology Transfer Support Fund, ORIC UVAS, Lahore. 19th November- 2020.
  2. How to Manage Your References Using Refworks, Organized by ProQuest and Higher Education Commission, Islamabad. 26th October 2020.
  3. Intellectual Property Rights and Requirements of Patent Filing, UVAS, Lahore. 2019.
  4. 1st National Conference on Sterile Compounding and Antiseptic Techniques ‘‘A Special focus on Handling of Hazardous Materials’’ Organized by IPS, UVAS, Lahore. 2019.

 Trainings

 

 

Projects

As principal investigator

Sr. No

Title of Project

Co-PI Program

Amount

Status

1.

Development of transdermal nanofilm containing fluticasone propionate against psoriasis and its In-vitro, in-vivo correlation

Dr. Khurram Waqas

0.5 million

completed

2.

Development of sustain release drug loaded biodegradable film for regeneration of diabetic ulcer

Dr. Fatima Rasool

27 million

Applied

As co-PI

 

 

 

 

 

Sr. No

Title of Project

Co-PI Program

Amount

Status

1.

Development and production of bio-pesticides for the control of tick infestation in cattle in Pakistan

Dr. Muhammad Oneeb

19.42 million

Applied

Laboratory Development

Development of new courses

Sr. No.

                Course No.

                       Course Title

                Class

      Credit Hours