Usman-Mu-03

Contact information

Email: usman.ips@uvas.edu.pk
Cell: +923334548265
Phone: +92 42 99211449
Ext. 314
Dr. Muhammad Usman

Assistant Professor

B. Pharm (University of the Punjab, Pakistan),

M. Phil Pharmacology & Toxicology (UVAS, Pakistan),

PhD (University of Muenster, Germany)

Tel: +92-42-99214341
Mobile: +92-333-4548265
Email: usman.ips@uvas.edu.pk

HEC Approved Supervisor

Biography

Dr. Muhammad Usman, is Assistant Professor at Institute of Pharmaceutical Sciences (IPS), University of Veterinary & Animal Sciences, Lahore, Pakistan. He got B.Pharmacy degree from University of the Punjab in 2005 and M.Phil in Pharmacology and Toxicology from University of Veterinary and Animal Sciences, Lahore in 2008. He went to Germany in 2013 and completed his doctoral degree in December 2016 from University of Muenster, Germany.
He started his professional career in Feb 2006 as Community Pharmacist and served at Himont Pharmacy Gujranwala as Branch Manager for 9 months. Then he joined Doctor’s Hospital and Medical Centre as retail Pharmacist on 02-11-2006 and worked till 07-11-2008.
Immediately after completion of his M.Phil in 2008 he joined Institute of Pharmaceutical Sciences, UVAS as Lecturer on 08-11-2008 and was a member of pioneer team in the establishment of this esteemed Institute.
He is also a part of Bioequivalence Study Center (BeSt Center), UVAS, Lahore. He is skillful in conducting clinical trials for Bioequivalence studies and quantification of drugs in biological fluids through HPLC.
The research title of his M.Phil Thesis was “Comparative pharmacokinetics of Levofloxacin in Healthy Volunteers and in Patients Suffering from Typhoid Fever”. During M.Phil he got hands on training of clinical trials and quantification of drug concentrations in human plasma by using HPLC.
The area of research in Doctoral study is Population Pharmacokinetics in Elderly Patients. He got a good experience of working on different Pharmacokinetic software including NONMEM® and PK-Sim®. He is the Pioneer Pharmacometrician who is introducing this technique in Pakistan and has developed Pakistan’s 1st ever Pharmacometrics Laboratory at IPS, UVAS.

Dr. Muhammad Usman is representing Pakistan in Asian Pharmacometrics Network (APN) as Board member. He has also represented Pakistan as Pharmacometrician at different scientific forums in Pakistan and across the globe.

Area of Interest

  • Population Pharmacokinetics (popPK) modelling
  • Physiologically Based Pharmacokinetics (PBPK)
  • Quantification of drug concentrations in biological fluids by HPLC, LC-MS, Immunoassays
  • Quantification of drugs in blood by Dried Blood Spot (DBS) technique.
  • Bioequivalence studies
  • Pharmacovigilance
  • Availability of essential medicines

Publications

Research Grants

As Principal Investigator

Title

Funding agency Amount Status
Population Pharmacokinetics of Vancomycin in Pakistani Patients. Higher Education Commission of Pakistan

under Start Up Research Grant (SRGP) Program

PKR

0.5 Million

Completed
Population Pharmacokinetics of Antibiotics in Pakistani Patients. Higher Education Commission of Pakistan

Under National Research Program for Universities (NRPU)

PKR

1.983 Million

Completed

As Co-Principal Investigator

In-silico exploration of 6‑Substituted 2‑Arylaminopurines selectivity for CDK2 and CDK1 through Linear Interaction energy (LIE) and molecular dynamics simulations Higher Education Commission of Pakistan

under Start Up Research Grant (SRGP) Program

PKR

0.5 Million

Completed
Development of stem cell therapy for treating cutaneous wounds in canines: a translational model
for humans
Higher Education Commission of Pakistan

Under National Research Program for Universities (NRPU)

6.135 Million On Going
Determination of N-Nitroso dimethyl amine in amine-based anti-hypertensive drugs and their association with cancer Higher Education Commission of Pakistan

Under National Research Program for Universities (NRPU)

5.096 Million On Going

Professional Trainings

  1. Professional Competency Enhancement Program for Teachers (PCEPT) held at University of Veterinary and Animal Sciences, Lahore from Feb 02 to March 02, 2011. Organized by Higher Education Commission (HEC) of Pakistan, National Academy of Higher Education.
  2. Post Graduate Course for Higher Education Learning and Teaching (PGC-HELT) October 2020 to March 2021, organized by Faculty of Bio-Sciences, University of Veterinary and Animal Sciences, Lahore.

Membership of International Networks

Board member of Asian Pharmacometrics Network (APN) as representative of Pakistan

http://www.go-apn.org/company/company_05.php

Students Supervision

Student’s name

Thesis title

Status

Muhammad Ahmad Aaqib

(2017-VA-45)

Formulation development and evaluation of gastro-resistant tablet of ifosfamide using beta-cyclodextrin and hydroxylpropyl methylcellulose Completed

(2019)

Muhammad Muaaz Munir

(2011-VA-729)

Population pharmacokinetics of vancomycin in Pakistani patients Completed

(2019)

Muhammad Noman Akram

(2011-VA-731)

Therapeutic drug monitoring of vancomycin through validated HPLC method Completed

(2020)

Ammara Arif

(2012-VA-732)

Population pharmacokinetics of moxifloxacin in Pakistani patients Completed

(2020)

Syeda Zia-ul-Ain Bukhari

(2018-VA-65)

Simultaneous quantification of moxifloxacin and linezolid in human plasma using HPLC Completed

(2020)

Asim Ali

(2011-VA-728)

Formulation development and in-vitro characterization of solid dispersion tablets of carbamazepine for enhancing bioavailability Completed

(2021)

Syed Ehsan ul Haq

(2019-mphil-1176)

Population pharmacokinetics of Vancomycin in elderly patients from pooled clinical data Completed

(2021)

Faiza Urooj

(2019-mphil-1179)

Risk based prioritization of essential antimicrobial agents based on BCS classification and review of bioanalytical methods for mandatory bioequivalence status Completed

(2021)

Hammad Ahmad

(2019-mphil-1205)

A comparative study on non-prescription dispensing of antibiotics and narcotics at drug sale outlets in urban areas of Lahore Completed

(2021)

Annum Maha

(2019-mphil-2141)

Population Pharmacokinetics of linezolid in Pakistani Patients Completed

(2022)

Akasha Jamshaid

(2015-VA-294)

Impact of pharmacist's interventions in ensuring therapeutic outcomes of anti-tuberculosis drugs in TB patients with comorbidities in a public sector health facility Completed

(2022)

As Co-Supervisor
Student’s name Thesis title Status
Rabia Saleem

(17-M/LCWU-16)

Population pharmacokinetics of ciprofloxacin among indoor patients of tertiary care hospitals, Lahore, Pakistan

 

Completed

(2020)

Madiha Zaman

(17-M/LCWU-11)

population pharmacokinetics of meropenem among post-operative patients

 

Completed

(2020)

Qurrat-ul-Ain Yousaf

(17-M/LCWU-14)

Comparative population pharmacokinetics of valproic acid in Pakistani patients and Korean patients

 

Completed

(2020)

Sitaram Khadka

15-MCol-M19a

 

Comparative pharmacokinetics of meropenem in young and elderly patients through a non-linear mixed effect modelling approach Completed

(2022)

As Member of Supervisory Committee

Student’s name

Thesis title

Status

Muhammad Shahwar

(2009-VA-017)

Evaluation of Good Pharmacy Practice in

Community  Drug Sale outlets with "A" Category License in the Urban Lahore.

Completed

(2011)

Asad Ali Lodhi

2009-VA-343

Study for detection, evaluation, and strategies to minimize medication errors in tertiary care teaching hospitals Lahore Completed

(2019)

Rehan Ali

2009-VA-343

Comparison of in-vitro drug release of different brands of Co-amoxiclave using HPLC method Completed

(2019)

Qurrat-ul-Ain Khan

2017-VA-98

Development and characterization of orodispersible film containing cefixime trihydrate as a model drug Completed

(2019)

Sadaf Aroosa

2017-Mphil-1591

Impact of dexmedetomidine infusion on isoflurane induced oxidative stress and DNA damage in patients undergoing major emergency surgery Completed

(2019)

Iffat Akhtar

2013-VA-291

Investigation of efficacy of complementary and alternative medicine for peripheral arterial disease: A systematic review and meta-analysis Completed

(2021)

Yasmeen Iqbal

2019-mphil-1182

Population Pharmacokinetics of meropenem in adult patients from pooled clinical data Completed

(2021)

Zunair Maqsood

2019-mphil-1185

Challenges and Opportunities in sustainability of Bioequivalence  Study Centers in Pakistan Completed
Asma Rabail

2019-mphil-1188

Formulation of Doxorubicin loaded PLGA Nanoparticles for gastric cancer using Thiolated Hydroxy Ethyl Cellulose Completed

(2021)

Muhammad Bilal Saeed

2020-VA-308

Impact of interventions by ward pharmacist in tertiary care teaching  hospital on medication use pattern and safety using action research

 

On Going
Umaira Israr

2020-VA-1484

Prices, availability, and affordability study of essential antifungal, antiviral and antiparasitic medicines in Lahore, Pakistan using WHO/HAI Methodology

 

Completed

(2022)

Nawal Nida

2014-VA-158

Analysis of drug-drug interactions in outpatient department of charity based hospital Completed

(2022)

Muhammad Chaudhry

2014-VA-137

Formulation of thiolated mucoadhesive intravesical nanpoparticles for bladder cancer Completed

(2022)

Laboratory Development

Developed Pakistan’s first Pharmacometrics lab for carrying out research on Population Pharmacokinetic (popPK) modelling, Pharmacokinetic Pharmacodynamic (PKPD) modelling and Physiologically Based Pharmacokinetic (PBPK) modelling.

Development of New Courses

Sr. No.

                Course No.

                       Course Title

                Class

      Credit Hours

1

PHCU 1021

Population pharmacokinetic Modelling

M.Phil (Pharmaceutics)

3(2-1)