Mr. Muhammad Shoaib Ali Gill

PhD (Pharmaceutical Chemistry) Monash University
Lecturer

Tel: 92-42-99214341 
Email: shoaib.gill@uvas.edu.pk

Biography

I am currently working as lecturer at Institute of Pharmaceutical Sciences (IPS), University of Veterinary and Animal Sciences (UVAS), Lahore. My academic and research career spans almost 10 years and my primary interest of research are molecular synthesis, computer aided drug design, natural product and medicinal chemistry. I received my Doctorate from School of Pharmacy, Monash University Malaysia working on the project titled; “Design and development of new anti-HIV agents based on quinolone Scaffolds”. During this research project I collaborated with some of the best drug research institute in the world like Rega Institute, KU Leuven, Belgium. I undertook multiple step synthesis involving complex heterocyclic chemistry. I tailored a very efficient, low-cost and eco-friendly synthetic methodology, specifically for Quinolone carboxamide synthesis. I performed cytotoxicity and anti-proliferative assays against some selected compounds. I have supervised 6 M.Phil students and trained the juniors at my PhD lab.

Areas of Interest

1. Teaching and research in pharmacy subjects
2. Molecular synthesis and Modification
3. Computer aided Drug Design
4. Phytochemical isolation and semi-synthesis
5. Anti-microbial testing and biological assays

Publications                

2022

• Gill, M.S.A., Azzman, N., Hassan, S.S., Shah, S.A.A. and Ahemad, N., 2022. A green and efficient synthetic methodology towards the synthesis of 1-allyl-6-chloro-4-oxo-1, 4-dihydroquinoline-3-carboxamide derivatives. BMC chemistry, 16(1), p.111.

2020

• Gill, M.S.A., Saleem, H. and Ahemad, N., 2020. Plant extracts and their secondary metabolites as modulators of kinases. Current topics in medicinal chemistry, 20(12), pp.1093-1104.

2019

• Gill, M.S.A., Hassan, S.S. and Ahemad, N., 2019. Evolution of HIV-1 reverse transcriptase and integrase dual inhibitors: Recent advances and developments. European journal of medicinal chemistry, 179, pp.423-448.

2018

• Mahmood, W., Saleem, H., Ahmad, I., Ashraf, M., Gill, M.S.A., Ahsan, H.M., Chaman, S., Abbas, S., Mubashar, A., Khan, S.U. and Ahemad, N., 2018. In-vitro studies on acetylcholinesterase and butyrylcholinesterase inhibitory potentials of aerial parts of Vernonia oligocephala (Asteraceae). Tropical Journal of Pharmaceutical Research, 17(12), pp.2445-2448.

2017

• Shahid, N., Adnan, S., Farooq, Gill, M.S.A., Shabbir, M., Masood, Z., Waqar, K., Saleem, H., Gill, S.A. and Ali, T., 2017. Development of compressed coated polypill with mucoadhesive core comprising of atorvastatin/clopidogrel/aspirin using compression coating technique. Acta Poloniae Pharmaceutica, 74(2), pp.477-487.

2016

• Saleem, H., Ahmad, I., Shahid, M.N., Gill, M.S.A., Nadeem, M.F., Mahmood, W. and Rashid, I., 2016. In vitro acetylcholinesterase and butyrylcholinesterase inhibitory potentials of Jatropha gossypifolia plant extracts. Acta Poloniae Pharmaceutica, 73(2), pp.419-423.

• Saleem, H., Ahmad, I., Ashraf, M., Gill, M.S.A., Nadeem, M.F., Shahid, M.N. and Barkat, K., 2016. In vitro studies on anti-diabetic and anti-ulcer potentials of Jatropha gossypifolia (Euphorbiaceae). Tropical journal of pharmaceutical research, 15(1), pp.121-125.

• Saleem, F., Khan, M.T.J., Saleem, H., Azeem, M., Ahmed, S., Shahid, N., Gill, M.S.A., Nadeem, F., Ali, T., Altaf, H. and Mehmood, W., 2016. Phytochemical, antimicrobial and antioxidant activities of Pteris cretica L.(Pteridaceae) extracts. Acta Poloniae Pharmaceutica, 73(5), pp.1397-403.

• Saleem, H., Ahmad, I. and Gill, M.S.A., 2016. Evaluation of lipoxygenase inhibition of Jatropha gossypifolia, a medicinal plant from Pakistan. Bangladesh Journal of Pharmacology, 11(2), pp.319-320.

• Chuman, S., Saleem, H., Gill, A., Shahid, N.A.B.E.E.L., Karamat, F., Ali, T., Nadeem, F.A.I.S.A.L. and Mehmood, W., 2016. Evaluation of spermicidal property of Hippophae rhamnoides l. Berries. Acta Poloniae Pharmaceutica, 73(6), pp.1665-1668.

2015

• Saleem, H., Ahmad, I. and Gill, M.S.A., 2015. Phytochemical screening and diuretic activity of Euphorbia granulata. Bangladesh Journal of Pharmacology, 10(3), pp.584-587.

Trainings and Workshops Attended   

• Two day hands-on training workshop on Drug Discovery in Modern Era held on 20th-21st March, 2023 at Khawaja Farid Campus, The Islamia University Bahawalpur.

• Hybrid workshop on NMR Spectroscopy for the Analysis of Small Organic Molecules on 27th July, 2022. Organized by The American Chemical Society Monash University Malaysia International Student Chapter hosted by School of Pharmacy, Monash University Malaysia.

• Hands-on Workshop: Cell Culture and In-Vitro Human Disease Models, from 27th-28th November, 2019 at Co-organized by Jeffrey Cheah School of Medicine & Health Sciences and School of Pharmacy, Monash University Malaysia.

• Scientific Writing Workshop from 30th-31st October, 2019 at Organized by Campus Research Management (CRM) and School of Pharmacy, Monash University Malaysia.

• Mass Spectrometry Applications and Data Analysis Workshop, on 21st–22nd August, 2019 at Monash University Malaysia. Co-organized by Agilent technologies SDN. BHD.

• NMR-WORKSHOP: Structural Elucidation of Small Molecules by Nuclear Magnetic Resonance Spectroscopy, 23rd–24th July, 2019. Organized by Bruker and sponsored by The American Chemical Society Monash University Malaysia International Student Chapter hosted by School of Pharmacy, Monash University Malaysia.

• Microwave Technologies and the Update in Research Seminar, (Applications of microwave assisted heating in molecular synthesis and isolation). 6th February, 2018 at School of Pharmacy, Monash University, Malaysia. Co-organized by Anton Paar Sdn. Bhd. Malaysia.

• Five days’ workshop on “Research Methodologies Using Statistical Techniques in Biological Sciences” from 17th-23rd December, 2015 organized by Department of Statistics and Computer Science, Faculty of Life Science and Business Management at University of Veterinary and Animal Sciences, Lahore, Pakistan.

• Training workshop of online Microsoft office 365. Higher Education Commission of Pakistan. Seminar hall of University of Veterinary and Animal Sciences, Lahore, Pakistan, 11th May 2015.

• Pre-Servise Competency Enhancement Training for Teachers (P-SECTT). Organized by Center for Educational Policy and Administration (CEPA), University of Veterinary and Animal Sciences (UVAS), Lahore on 4th-9th August, 2014.

 

Conferences and Seminars Attended             

• One day seminar on “Unveiling Nature's Remedies through Pharmaceutical Analysis”. Organized by Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, 23rd May, 2023. (Co-Organizer).

• MONASH INITIATE 2021 (Virtual conference), The Inaugural Monash International Health Science and Technology Conference. Themed “Inspiring Innovation via Multidisciplinary Collaboration”. 16th-17th June, 2021. E-poster presentation titled “A green and efficient approach to the synthesis of N-substituted 4-Quinolone carboxamides”. (Poster presentation)

• 4th International Conference on Pharmacy and Pharmaceutical Sciences, held in Bangkok, Thailand on 13th-14th December, 2019. Themed: “Innovative Approaches, analysis and Developments in Pharmacy and Pharmaceutical Science”. Oral abstract titled “Design and development of anti-HIV agent based on Quinoline scaffold”. (Presenter).

• 19th International Pharmacy Conference & Exhibition. Themed; Emerging role of pharmacist and pharmacy in public health, 21st-24th April, 2016 - Pearl Continental Hotel, Lahore, Pakistan. (Participant)

• 37th All Pakistan Science Conference “Food Safety and Security Challenges in Pakistan” , organized by Pakistan Council of Scientific and Industrial Research (PCSIR) Labs, Firozpur Road, Lahore, from 16th to 17th November, 2015. (Participant)

• Participation in one day Seminar on “Donate blood, Save Life” Organized by Blood Donor Society IPS, UVAS, November, 2015.

• Participation in one day Seminar on “Navigating Future of Community Pharmacy in Pakistan” organized by Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, 1st October, 2015.

Research Interest

• Development and exploration new synthetic methodologies for small molecular synthesis.
• Synthesis and biological evaluation of novel compounds.
• Chemical characterization and spectral analysis.
• Lead optimization and computationally guided modification of lead compounds.
• Virtual screening, Molecular modelling, Docking, Molecular Dynamic (MD) simulation, and 3D-QSAR studies.
• Working experience with specialized computational software and tools for Computer Aided Drug Design like Auto-Dock suit, GOLD, Biovia Discovery studio, Various Molecular modelling and drug discovery tools by OpenEye scientific, Schrodinger maestro and Gausian.
• Isolation and biological evaluation of natural products.
• Use of AI tools in research and academic applications.

Research Projects and grants

• Design and Synthesis of new Anti-HIV agents based on Quinolone scaffold. (2018-2023).

Funding agency(s):     

• Fundamental Research Grant Scheme (FRGS), Ministry of Higher Education (MoHE), Malaysia. (2020-2023).
• 2018-2020 Seed Grant, Tropical Medicine & Biology (TMB) Multidisciplinary Platform, Monash University Malaysia. (2018-2020).

Role: Team member.
Project Amount:       FRGS funding USD 26000/-
TMB seed funding USD 6000/-